Amytracker是用于蛋白质聚集体的高质量可视化的荧光示踪分子。当与样品中的目标结合时,分子会变得鲜艳多彩——高度荧光。目标是淀粉样蛋白或含有淀粉样蛋白原纤维和原纤维的蛋白质聚集体。因此,使用Amytracker,您可以对来自各种物种组织中的各种淀粉样蛋白或肽的淀粉样蛋白的早期、原纤维状态进行可靠的荧光染色,并对液体样品中的蛋白质聚集体进行纤维化测定和分光光度法检测.nAmytracker are fluorescent tracer molecules for high-quality visualization of protein aggregates.The molecules become vividly colorful – highly fluorescent - when bound to a target in a sample. Targets are amyloids or protein aggregates containing amyloid fibrils and proto-fibrils. Therefore, using Amytracker, you can achieve reliable fluorescent staining of early, pre-fibrillar states of amyloids arising from a variety of amyloidogenic proteins or peptides in tissues from a wide range of species and perform fibrillation assays and spectrophotometric detection of protein aggregates in liquid samples.
产品描述
Amytracker:检测淀粉样蛋白和其他蛋白质聚集体,用于研究人员和医生对许多神经退行性疾病,包括阿尔茨海默病有更深入的了解。nAmytracker molecules are non-toxic and are readily taken-up when applied to cells in culture. Further, they are photo- and thermostable and allow for easy handling in any application. Our ex vivo products will simplify your life when performing staining of tissue sections, live-cell imaging or fibrillation assays. The ex vivo products are available in aliquots of 50 µl, 100 µl, 150 µl or 200 µl (all delivered in 50 µl vials). Please, contact us to find out more about Amytracker for in vivo use.nAmytracker 480 (Excitation: 405-458 nm, Emission: 470–550 nm, Emax = 480 nm)nAmytracker 520 (Excitation: 405-488 nm, Emission: 500-600 nm, Emax = 520 nm)nAmytracker 540 (Excitation: 430-500 nm, Emission: 530-600 nm, Emax = 540 nm)nAmytracker 630 (Excitation: 458-514 nm, Emission: 600-650 nm, Emax = 630 nm)nAmytracker 680 (Excitation: 530-565 nm, Emission: 600-800 nm, Emax = 680 nm)